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Professional & Aesthetic · Cream & Serum

Apexium

A finished professional serum-and-cream system built on the Apexium EX3-MP Complex™ — plant-derived exosomes paired with a multi-peptide + collagen matrix. Documented on 28-day human evaluation.

  • EX3-MP peptide matrix + plant-derived exosome carrier
  • Skin moisture +72.11% · TEWL −16.36% at 28 days (p<0.001)
  • Eye-area wrinkle area −10.22%; 93.94% rated suitable for sensitive skin
  • Animal-free, non-immunogenic collagen · GMP-certified
Apexium Cellular Regenovation Serum — 40 ml bottle
Apexium · Serum 40 ml
01SpecificationsThe full spec sheet
Classification
Finished cosmetic (professional skincare system)
Intended use
Professional, appearance-focused skincare regimen
Not intended for
Injection or medical treatment
Complex
Apexium EX3-MP Complex™ — plant-derived exosomes + collagen-peptide matrix
Actives
Loaded exosomes · Type IIIα human-homologous collagen · bioactive collagen peptides · hyaluronic acid · Natural Moisturizing Factors
Peptides
Acetyl Hexapeptide-8 · Dipeptide Diaminobutyroyl Benzylamide Diacetate · Palmitoyl Peptides
Mechanism
Activation (serum) → Rejuvenation → Protection (cream)
Clinical study
28-day human evaluation on sensitive, dry, photoaged skin
Provenance
Animal-free · non-immunogenic · GMP-certified facility
Formats
Serum 40 ml · Cream 50 g · Set
Marking
EX3-MP Complex · Made in USA
Storage & handling
Provided with product documentation
Shelf life
Stated on pack and documentation
Minimum order
On request by market
Lead time
Confirmed with each quote
02Clinical evaluation28-day human study · biomarkers & benefits

Documented on skin,
measured to the biomarker.

Subjects with sensitive, dry, or photoaged skin used the Apexium regimen for 28 days. Endpoints were captured with corneometry, TEWL, colorimetry, and image analysis; molecular effect was profiled by biomarker upregulation.

GainMed
CLINICAL EVALUATION
28-day human study
Sensitive · dry · photoaged
Apexium · Efficacy endpoints

Measured benefits

Deep hydrationSkin moisture content · corneometry
↑ 72.11%
p<0.001
Barrier repairTransepidermal water loss (TEWL)
↓ 16.36%
p<0.001
Anti-wrinkleEye-area wrinkle area · image analysis
↓ 10.22%
p<0.05
SoothingSkin redness (a* value) · colorimetry
↓ 1.88%
p<0.05
Sensitive-skin toleranceSelf-assessed suitability
93.94%
Agreed
Signed by clinical PI Request the full study

Molecular
upregulation.

In-vitro profiling on human keratinocytes and fibroblasts. Apexium significantly upregulated the essential proteins that keep the barrier intact and the dermis structured.

Loricrin (LOR)
↑ 90.91% — cornified envelope; strengthens the barrier
Filaggrin (FLG)
↑ 22.73% — produces Natural Moisturizing Factors for hydration
Transglutaminase-1 (TGM1)
↑ 113.89% — cross-links barrier proteins for structural integrity
CD44
↑ 89.19% — enhances hyaluronic-acid utilization for plumpness
Type I & IV collagen
↑ 36.76% – 58.18% — rebuilds dermal structure and strengthens the DEJ

Endpoints are illustrative of the referenced study. Individual response varies with age, skin type, and adherence. Not a therapeutic claim.

03DocumentationWhat ships with each batch

Documentation
available.

Request any of the following for Apexium. We share what applies to your market and intended use.

  • Product overviewon request
  • Ingredient / INCI profileon request
  • Formulation contexton request
  • Usage guidanceon request

Cosmetic classification

Apexium is a finished cosmetic for professional skincare. It is for external use on intact skin and is not intended to diagnose, treat, cure, or prevent any disease. Claims are limited to appearance and skin-conditioning benefits, and market registration requirements vary by country.

04 In practice Documented user photography

Before & after,
on the record.

Documented on a single subject after 90 days of the Apexium regimen — serum plus cream, twice daily — under matched studio lighting.

Split-face photograph documenting appearance before and after a 90-day Apexium regimen
Fig. 03 · 90-day regimen Same subject · matched lighting · individual response varies with age, skin type, and adherence. Not a therapeutic claim.
05Also in the portfolioRelated materials

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